Welcome to Lotz Lab


The University of California at San Francisco Laboratory for Orthopaedic Bioengineering is directed by Jeffrey C. Lotz, Ph.D . The laboratory is located within the Department of Orthopaedic Surgery and aims to understand the biomechanics and biology of the lumbar spine and intervertebral disc in both health and disease. A number of research programs in this area include: theoretical and experimental development of material laws for disc tissues; finite element simulations of disc and vertebral body response to in vivo loading; animal models to clarify the mechanisms of disc degeneration and repair; animal models to clarify the relationship between disc degeneration and pain; investigation of novel surgical interventions meant to treat back pain; and tissue engineering of fibro-cartilaginous tissues. 

Dr. Jeff Lotz and Dr. Devante Horne in the Bone Lab