CDMI logoCenter for Disruptive Musculoskeletal Innovations 

A National Science Foundation Industry & University Cooperative Research Center

The Center for Disruptive Musculoskeletal Innovations (CDMI) represents an exciting and novel integration of healthcare economics, biomedical science, and clinical medicine. University faculty and industry partners are able to collaborate to target novel technologies that will decrease healthcare costs and improve the management and life of patients with musculoskeletal disease.

The mission of the CDMI is to facilitate collaborations between experts in healthcare economics, biomedical science, and clinical medicine to analyze data and inform new technology development that is rationally targeted at value creation and cost reduction, thereby enhancing probabilities for eventual regulatory approval, payor reimbursement, and clinical adoption.


Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration


The Center for Dental, Oral, & Craniofacial Tissue & Organ Regeneration (C-DOCTOR) is one of two national NIDCR-funded Tissue Regeneration Resource Centers. C-DOCTOR is a partnership among several California institutions to recruit, nature, and translate promising tissue regeneration technologies to human clinical trials. Participating universities include: UC San Francisco, UC Berkeley, UC Davis, UC Los Angeles, University of Southern California, and Stanford University.

Our vision is to assemble a comprehensive and dynamic team of clinicians, research scientists, biostatisticians, regulatory scientists, and pre-clinical/clinical trial experts to enable the development and clinical implementation of innovative approaches for dental, oral, and craniofacial tissue regeneration.


Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain


The Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain (REACH) is a $30M NIH-funded Mechanistic Research Center that is part of the NIAMS Back Pain Consortium Research Program (BACPAC) under the HEAL Initiative to stem the national opioid health crisis. BACPAC was funded to support studies in chronic low back pain (cLBP) since it is the most common, non-cancer reason for opioid prescription in the US. REACH is an interdisciplinary consortium of basic and clinical scientists dedicated to developing precision medicine approaches for managing cLBP that factor in the interconnection between biology, biomechanics, psychology, and socio-environmental factors.